September 27, 2011

Can Resveratrol Replace Exercise?

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September 27, 2011
Bottom Line's Daily Health News
In This Issue...
  • Maintain Healthy Blood Sugar and Get Complete Nutrition -- All At One Affordable Price!!
  • Can Resveratrol Replace Exercise?  
  • These 4 Things Happen Right Before a Heart Attack
  • Bring the Doctors Back to the Hospitals!
  • Pregnancy Advice I Never Read, But Always Share

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Can Resveratrol Replace Exercise?

It is beginning to seem as if some people believe that resveratrol, a plant polyphenol found in red wine (among other places), might be a real-life magic potion -- given that research has shown it can slow tumor growth, improve heart health, heal inflammation-related damage and slow the ravages of aging. And now here comes another study suggesting that it may be able to hold back the damage that is done when people don’t exercise!

You know me well enough to know that I won’t be singing the praises of any pill that justifies sitting on the couch watching TV instead of living a healthy, active lifestyle -- but there are times (such as when we are ill or injured or have overloaded schedules) when we just can’t exercise. In that light, I think this new research is quite important.

Space-Age Findings

Let me start by saying this is sort of an "out there" study that was inspired by space travel and involved rats -- weightless ones, yet. Even so, it’s intriguing.

The study: In an effort to examine the damage that weightlessness causes for astronauts spending long periods in space, which includes loss of muscle and bone, researchers at the University of Strasbourg, France, suspended rats to approximate weightlessness. The rats were unable to move about as they usually do (though they were able to eat and drink normally). Half of these rats were dosed daily with resveratrol. After 15 days, the rats that had not received resveratrol were experiencing all the predictable problems, including loss of strength, muscle mass and bone density. They also developed insulin resistance, a precursor to diabetes. The resveratrol-taking rats, however, did not show any of these effects.

What’s In It for You?

So resveratrol is obviously tremendously good for rodents that don’t exercise… but is it reasonable to believe this is relevant to human beings when we don’t exercise?

To get information on this, I called Heather Hausenblas, PhD, an exercise psychologist and resveratrol researcher at the University of Florida and scientific adviser for ResVitále, a company that makes resveratrol products. Dr. Hausenblas and her colleagues recently completed a review of the human clinical studies already done on resveratrol. She told me that findings from the weightless-rats study are in line with earlier studies that show resveratrol is a powerful antioxidant that has antiaging, anticarcinogenic and anti-inflammatory properties with few, if any, negative side effects. But no one is sure how or why resveratrol is so powerful, so more research needs to be done.

In the meantime, though, it’s not surprising that resveratrol is becoming such a popular supplement. It is not easy to get from food sources -- though red wine, grape juice, grapes and berries and, surprisingly, peanuts contain resveratrol, the amounts are not even close to the quantity that studies indicate would have helpful properties.

Take This List and Shop with It

There now are dozens of resveratrol supplement brands on the market, but Dr. Hausenblas cautions that consumers should beware. You need to check the label carefully to be sure that the brand you choose is a high-quality product. The label should show the following...
  • The product doesn’t contain fillers or additives, such as sugar, starch, gluten or artificial colors or flavors. These other ingredients make it easier and cheaper for the manufacturer to produce resveratrol supplements but do not add any health value. Look for products that contain "trans" not "cis" resveratrol -- trans resveratrol is the bioactive form of the resveratrol polyphenol that has been scientifically proven to enhance cellular productivity, Dr. Hausenblas told me. She added that it has also been shown to increase the number of mitochondria in cells, thus boosting energy capacity.
  • The product was produced under "good manufacturing practices" (or GMP), which are standards established by the US Food and Drug Administration to which manufacturers adhere on a voluntary basis. These standards are intended to ensure that products are consistently produced with high-quality ingredients.
Also, resveratrol is light-sensitive, so it should be protected in opaque capsules and in a bottle that shields the capsules from light.

The Daily Dose

Dr. Hausenblas said that research hasn’t yet pinned down what an optimal dose of resveratrol is nor who would benefit most from taking it, but she said there is enough research to indicate that a dosage of up to 500 mg a day is helpful for most people. Since the body absorbs resveratrol rapidly and its activity is fairly short-lived, she suggests splitting the daily dosage into two smaller ones that will keep some in the body most of the time. Resveratrol is safe, Dr. Hausenblas said, but she suggests starting with a low dosage so your body can adjust to it gradually -- some people experience digestive upset at first. Also, pregnant women, nursing mothers and people with a medical condition should check with the doctor before taking resveratrol to be sure it is appropriate for them.

Source(s):

Heather Hausenblas, PhD, an exercise psychologist and resveratrol researcher at University of Florida, Gainesville.

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Bring the Doctors Back to the Hospitals!

Once upon a time, hospitals were run primarily by physicians, but there’s been a real turnaround, and today MDs head just 235 of the nation’s nearly 6,500 hospitals. The rest of the institutions are led by business-trained administrators -- even though physician-led hospitals outscore all others by 25% in standard quality measures, according to a study in the June 25, 2011 issue of Social Science & Medicine. What the results tell me: It may be time to turn back the clock, given the improved outcomes of doctor-run hospitals.

Is There a Doctor in the House?

The background: At the Institute for the Study of Labor in Bonn, Germany, investigators constructed a database of the top 100 US medical centers for cancer care, digestive disorders and heart surgery based on 2009 US News and World Report hospital rankings. These rankings, designed to help consumers determine where to seek the best care, focused on:

Structure: How many nurses a hospital has, availability of key technologies, presence of a trauma center, etc.

Process: The delivery of care, which encompasses diagnosis, treatment, prevention, patient education and length of stay.

Outcomes: How many people die within 30 days of discharge.

Patient safety: How many accidental adverse events occur and how up-to-date medical procedures are.

Next, the researchers collected data on each hospital chief executive officer (CEO). They placed CEOs in one of two categories -- physician or nonphysician. Analyzing the association between doctor-run and administrator-run hospitals, the team found that:

Overall, hospital quality scores were 25% to more than 30% higher when a doctor was at the helm. For instance, when it came to cancer care, physician-led hospitals outperformed others by 33%.

In the US News "honor roll" of highest ranking hospitals, 16 out of 21 CEOs were MDs.

Of course, it should not be such a surprise that doctors are more effective at leading medical institutions.

Physicians who have spent time at the bedsides of critically ill patients have a better understanding of what works in the hospital and what doesn’t, notes Barry Silbaugh, MD, CEO of the American College of Physician Executives (ACPE), the nation’s largest medical management educational association for physicians. When MDs bring that experience to the executive suite, it makes a difference. Of course, not all doctors -- even good ones -- are cut out to be CEOs. But Dr Silbaugh notes that about half of all medical schools now make leadership training and management part of their curricula. The ACPE also offers advanced leadership courses for doctors. With the proper management and business training, doctors can balance financial concerns with patient care in a way that many nonphysician CEOs simply would not be able to.

While some fine medical centers are run by business school grads with MBAs, this study suggests that your odds of getting the best possible treatment are greater at doctor-run institutions -- one more factor to take into account before checking yourself into a hospital.

Source(s):

Barry Silbaugh, MD, FACPE, CEO, American College of Physician Executives (ACPE), Tampa, Florida. The ACPE is the nation’s largest medical management educational association for physicians. Dr. Silbaugh is on the Board of Governors of the National Patient Safety Foundation and was named to Modern Healthcare’s 100 Most Powerful People in Healthcare list for 2009. He is coauthor of "Landing on the Hudson River: Lessons for Health Care" (an article that appeared in Physician Executive, May 2010) with Jeff Skiles, the copilot of Flight 1549, which outlines key principles of safety and teamwork important to health care.

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Pregnancy Advice I Never Read, But Always Share

Who can resist giving a pregnant woman advice? No woman I know who has gone through it herself. I certainly can't. In fact, I was sharing my advice just yesterday with a friend's daughter-in-law, who told me she thought I should write a pregnancy book. Well, I don't have that many pointers, but those that I do share are apparently uncommon. These tips were tremendously helpful to me and have become helpful to countless others.

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Be well,


Carole Jackson
Bottom Line's Daily Health News


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